CDCA7L

Across TCGA patient cohorts, CDCA7L mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCA7L-associated genes across cancer lineages are mTOR_pS2448, p27_pT198, and PCNA. Each is linked with CDCA7L in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCA7L-to-partner and partner-to-CDCA7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR_pS2448 grouped by CDCA7L-low versus CDCA7L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA7L→partner) and Y-score (partner→CDCA7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.177	-3.794	<.001	<.001	3	2
UCEC	p27_pT198 →	+0.078	+1.514	.031	.015	3	2
UCEC	PCNA →	+0.258	+2.137	<.001	.001	3	2
UCEC	ASNS →	+0.504	+2.222	<.001	.009	3	2
UCEC	ATM →	-0.483	-2.222	.001	.010	3	2
UCEC	4E-BP1 →	+0.443	+3.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

mTOR_pS2448 by CDCA7L expression — UCEC

Explore this box plot interactively →