CDCA7L

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CDCA7L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,077 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDCA7L-associated GO terms across cancer lineages are Positive regulation of chromosome separation, DNA strand elongation, and Regulation of cell cycle G2/M phase transition. Each is linked with CDCA7L in more than 11 cancer types. Because this analysis shows association rather than direction, both CDCA7L-to-partner and partner-to-CDCA7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome separation grouped by CDCA7L-low versus CDCA7L-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA7L→partner) and Y-score (partner→CDCA7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASPositive regulation of chromosome separation →+0.225+1.235<.001<.001312
UPPER_AERODIGESTIVE_TRACTDNA strand elongation →+0.181+1.585<.001<.001312
UPPER_AERODIGESTIVE_TRACTRegulation of cell cycle G2/M phase transition →+0.066+1.085.005.002312
PANCREASRegulation of mitotic sister chromatid separation →+0.190+1.293<.001<.001311
UPPER_AERODIGESTIVE_TRACTRegulation of cell cycle checkpoint →+0.125+1.374<.001<.001311
UPPER_AERODIGESTIVE_TRACTRegulation of metaphase/anaphase transition of cell cycle →+0.099+1.184.003<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

Positive regulation of chromosome separation by CDCA7L expression — PANCREAS

Box plot of Positive regulation of chromosome separation in CDCA7L-low vs CDCA7L-high samples in PANCREAS.

Explore this box plot interactively →

Exploration