CDCA7L

Across TCGA cell cohorts, CDCA7L mutation is significantly associated with the RNA expression of many other genes, with 428 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDCA7L-associated genes across cancer lineages are CCDC134, CDH20, and BLOC1S6. Each is linked with CDCA7L in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCA7L-to-partner and partner-to-CDCA7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC134 grouped by CDCA7L-low versus CDCA7L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA7L→partner) and Y-score (partner→CDCA7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC134 →	+0.798	+3.212	.002	.006	3	1
LARGE_INTESTINE	CDH20 →	+0.080	+2.667	.002	.002	3	1
LARGE_INTESTINE	BLOC1S6 →	+0.477	+3.212	.005	.006	3	1
LARGE_INTESTINE	MINPP1 →	+0.633	+3.299	.002	.004	3	1
LARGE_INTESTINE	HINT3 →	+0.702	+3.212	.003	.006	3	1
LARGE_INTESTINE	BAG2 →	+0.970	+3.212	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

CCDC134 by CDCA7L expression — LARGE_INTESTINE

Explore this box plot interactively →