CDCA3

Across TCGA patient cohorts, CDCA3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,977 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDCA3-associated genes across cancer lineages are GMPS, PARPBP, and POLQ. Each is linked with CDCA3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CDCA3-to-partner and partner-to-CDCA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDCA3 versus GMPS in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA3→partner) and Y-score (partner→CDCA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPS →	+0.939	+0.621	<.001	<.001	3	5
LUAD	PARPBP →	+1.020	+0.650	<.001	.005	3	5
BRCA	POLQ →	+1.112	+1.050	<.001	<.001	3	5
HNSC	MSH2 →	+0.790	+0.712	.009	.002	3	5
LUAD	CDKN3 →	+1.318	+0.680	<.001	<.001	3	4
LUAD	VRK1 →	+0.699	+0.581	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,977 associations by consensus.

CDCA3 vs GMPS — LSCC

Explore this scatter interactively →