CDCA3

Across TCGA patient cohorts, CDCA3 mutation is significantly associated with the RNA expression of many other genes, with 812 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCA3-associated genes across cancer lineages are WRBP1, NMBR-AS1, and HMGN2P9. Each is linked with CDCA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCA3-to-partner and partner-to-CDCA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WRBP1 grouped by CDCA3-low versus CDCA3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA3→partner) and Y-score (partner→CDCA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	WRBP1 →	+0.249	+4.234	<.001	.008	3	2
SKCM	NMBR-AS1 →	+0.174	+4.513	<.001	.009	3	2
CESC	HMGN2P9 →	+0.166	+4.601	.004	.004	3	1
CESC	OR52N1 →	+0.029	+4.539	.001	.008	3	1
CESC	OR5T2 →	+0.034	+6.164	<.001	<.001	3	1
CESC	MIR107 →	+0.264	+5.837	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 812 associations by consensus.

WRBP1 by CDCA3 expression — CESC

Explore this box plot interactively →