CDCA3

Across TCGA cell cohorts, CDCA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,365 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDCA3-associated GO terms across cancer lineages are Regulation of mitotic sister chromatid separation, Nuclear division, and Chromosome localization. Each is linked with CDCA3 in more than 19 cancer types. Because this analysis shows association rather than direction, both CDCA3-to-partner and partner-to-CDCA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic sister chromatid separation grouped by CDCA3-low versus CDCA3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA3→partner) and Y-score (partner→CDCA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of mitotic sister chromatid separation →	+0.183	+1.505	<.001	<.001	3	20
BONE	Nuclear division →	+0.121	+1.789	.002	<.001	3	20
URINARY_TRACT	Chromosome localization →	+0.124	+1.577	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Spindle elongation →	+0.256	+1.593	<.001	.001	3	20
URINARY_TRACT	Metaphase chromosome alignment →	+0.134	+1.522	<.001	<.001	3	20
URINARY_TRACT	Mitotic sister chromatid segregation →	+0.118	+1.713	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,365 associations by consensus.

Regulation of mitotic sister chromatid separation by CDCA3 expression — URINARY_TRACT

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