CDCA2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CDCA2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CDCA2 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CDCA2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CDCA2 expression acts as an unfavorable survival marker.

UCEC, LSCC, and PDAC are the cancer types where CDCA2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSQuartileAll0.8641.000.01110view →
LSCCDFSMedianIII,IV0.8101.000.0128view →
PDACDFSTertileAll0.7430.900.0254view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration