CDCA2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDCA2 mutation is significantly associated with the RNA expression of many other genes, with 2,419 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCA2-associated genes across cancer lineages are RNU6-482P, MIR6738, and MIR8086. Each is linked with CDCA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDCA2-to-partner and partner-to-CDCA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA2→partner) and Y-score (partner→CDCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PRADRNU6-482P →+0.519+4.180.009.00933
SKCMMIR6738 →+0.391+1.709<.001.00533
BRCAMIR8086 →+0.331+3.844.008.00732
PRADEIF3JP1 →+0.220+4.797<.001.00332
COADCYCSP17 →+0.114+5.824<.001.00132
COADATP5MC1P8 →+0.389+4.542.002.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,419 associations by consensus.

Exploration