Across TCGA cell cohorts, CDCA2 mutation is significantly associated with the RNA expression of many other genes, with 466 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDCA2-associated genes across cancer lineages are CD300H, NLGN2, and TMEM256. Each is linked with CDCA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCA2-to-partner and partner-to-CDCA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA2→partner) and Y-score (partner→CDCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.020	+3.000	<.001	.003	3	2
BLOOD_Leukemia	NLGN2 →	+1.069	+3.321	.001	.005	3	2
BLOOD_Leukemia	TMEM256 →	+0.748	+3.442	.002	.001	3	2
BREAST	DEFB108B →	+0.176	+5.781	<.001	.001	3	1
LUNG_SCLC	LYZL2 →	+0.026	+5.643	<.001	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.745	+3.451	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 466 associations by consensus.

Exploration

CDCA2 survival (RNA) · tumor vs normal (RNA) · all CDCA2 data types