CDC73

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDC73 protein abundance is significantly associated with the RNA expression of many other genes, with 19,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC73-associated genes across cancer lineages are DHX9, EEF1AKNMT, and DARS2. Each is linked with CDC73 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDC73-to-partner and partner-to-CDC73 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC73 versus DHX9 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC73→partner) and Y-score (partner→CDC73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDHX9 →+0.965+0.341<.001<.001310
UCECEEF1AKNMT →+0.907+0.208<.001.00139
LSCCDARS2 →+0.773+0.342<.001<.00139
OVCENPF →+1.315+0.237<.001.00139
GBMKIF14 →+1.231+0.356<.001<.00139
LSCCCENPL →+0.754+0.347<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,216 associations by consensus.

CDC73 vs DHX9 — UCEC

Per-sample scatter of CDC73 vs DHX9 in UCEC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration