CDC7

Across TCGA patient cohorts, CDC7 protein abundance is significantly associated with the RNA expression of many other genes, with 10,187 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC7-associated genes across cancer lineages are FAM72B, KIF2C, and BUB1B. Each is linked with CDC7 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDC7-to-partner and partner-to-CDC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC7 versus FAM72B in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC7→partner) and Y-score (partner→CDC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM72B →	+1.047	+0.670	<.001	<.001	3	4
BRCA	KIF2C →	+1.520	+0.664	<.001	<.001	3	3
BRCA	BUB1B →	+1.397	+0.632	<.001	<.001	3	3
LSCC	CCDC34 →	+0.941	+0.751	<.001	<.001	3	3
HNSC	LINC02367 →	+0.958	+0.512	.001	.007	3	3
LSCC	OIP5 →	+0.834	+0.818	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,187 associations by consensus.

CDC7 vs FAM72B — BRCA

Explore this scatter interactively →