CDC6

Across TCGA patient cohorts, CDC6 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,764 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC6-associated proteins across cancer lineages are NCAPD2, NCL_S67, and NPM1_T199. Each is linked with CDC6 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDC6-to-partner and partner-to-CDC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC6 versus NCAPD2 in LUAD, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC6→partner) and Y-score (partner→CDC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCAPD2 →	+0.764	+1.413	<.001	<.001	3	10
LUAD	NCL_S67 →	+1.021	+1.304	<.001	<.001	3	10
LUAD	NPM1_T199 →	+1.467	+0.823	<.001	<.001	3	10
OV	NUF2_S247 →	+1.427	+1.018	<.001	<.001	3	10
LUAD	PAICS_S27 →	+1.423	+1.284	<.001	<.001	3	10
LSCC	RFC2 →	+0.464	+1.000	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,764 associations by consensus.

CDC6 vs NCAPD2 — LUAD

Explore this scatter interactively →