CDC42SE2

Across TCGA patient cohorts, CDC42SE2 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42SE2-associated genes across cancer lineages are MIR3713, SNRPGP7, and ELOA3DP. Each is linked with CDC42SE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42SE2-to-partner and partner-to-CDC42SE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3713 grouped by CDC42SE2-low versus CDC42SE2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42SE2→partner) and Y-score (partner→CDC42SE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3713 →	+0.619	+5.049	<.001	.002	3	2
UCEC	SNRPGP7 →	+0.467	+4.335	<.001	.007	3	2
LGG	ELOA3DP →	+0.019	+7.977	<.001	.007	3	1
LGG	RNU6-1076P →	+0.308	+7.977	<.001	.007	3	1
LGG	RNU6-592P →	+0.313	+7.977	<.001	.007	3	1
LGG	ARL2BPP7 →	+1.829	+7.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

MIR3713 by CDC42SE2 expression — UCEC

Explore this box plot interactively →