CDC42SE2

Across TCGA cell cohorts, CDC42SE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,661 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDC42SE2-associated GO terms across cancer lineages are T-helper 1 cell differentiation, Phosphatidylinositol-3-phosphate biosynthetic process, and Response to staurosporine. Each is linked with CDC42SE2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDC42SE2-to-partner and partner-to-CDC42SE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T-helper 1 cell differentiation grouped by CDC42SE2-low versus CDC42SE2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42SE2→partner) and Y-score (partner→CDC42SE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	T-helper 1 cell differentiation →	+0.119	+0.905	.002	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.059	+0.869	.002	.001	3	7
LARGE_INTESTINE	Response to staurosporine →	+0.156	+0.566	<.001	<.001	3	7
LARGE_INTESTINE	Cellular response to staurosporine →	+0.156	+0.566	<.001	<.001	3	7
STOMACH	Cell cycle switching, mitotic to meiotic cell cycle →	+0.569	+0.940	.009	<.001	3	7
STOMACH	Cell cycle switching →	+0.569	+0.940	.009	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,661 associations by consensus.

T-helper 1 cell differentiation by CDC42SE2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →