Across TCGA patient cohorts, CDC42SE1 mutation is significantly associated with the RNA expression of many other genes, with 1,518 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42SE1-associated genes across cancer lineages are IGKV1OR2-118, SRXN1, and CCL5. Each is linked with CDC42SE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42SE1-to-partner and partner-to-CDC42SE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42SE1→partner) and Y-score (partner→CDC42SE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1OR2-118 →	+0.236	+2.718	.002	.001	3	1
UCEC	SRXN1 →	+0.628	+3.638	.001	.001	3	1
UCEC	CCL5 →	+1.303	+3.606	.002	.001	3	1
UCEC	RBAK-RBAKDN →	+0.112	+2.405	<.001	.004	3	1
UCEC	MIR6075 →	+0.384	+3.415	<.001	<.001	3	1
UCEC	RNA5SP414 →	+0.766	+3.032	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,518 associations by consensus.

Exploration

CDC42SE1 survival (RNA) · tumor vs normal (RNA) · all CDC42SE1 data types