Across TCGA patient cohorts, CDC42SE1 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42SE1-associated genes across cancer lineages are Ku80, Notch1, and Caspase-7-cleavedD198. Each is linked with CDC42SE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42SE1-to-partner and partner-to-CDC42SE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42SE1→partner) and Y-score (partner→CDC42SE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.340	+2.183	.005	.035	3	1
UCEC	Notch1 →	+0.222	+3.321	.002	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.836	+2.999	.007	.035	3	1
UCEC	HER3_pY1289 →	+0.105	+3.348	.020	.005	2	1
UCEC	Caspase-8 →	-0.311	-3.321	.018	.010	2	1
UCEC	c-Jun_pS73 →	-0.196	-2.990	.018	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

CDC42SE1 survival (RNA) · tumor vs normal (RNA) · all CDC42SE1 data types