CDC42P3

Across TCGA pan-cancer cohorts, CDC42P3 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated CDC42P3 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CDC42P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CDC42P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ACC show a favorable association.

UCEC, UVM, and SKCM are the cancer types where CDC42P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.757	0.892	<.001	104	view →
UVM	DFS	Median	III,IV	0.255	0.765	<.001	81	view →
SKCM	OS	Median	III,IV	0.519	0.255	<.001	58	view →
KIRP	DFS	Tertile	III,IV	0.129	0.560	.002	42	view →
ACC	OS	Tertile	IV	1.000	0.370	.001	28	view →
STAD	DFS	Median	IV	0.155	0.565	.009	27	view →
MESO	DFS	Quartile	III,IV	0.268	0.520	.010	27	view →
LIHC	DFS	Tertile	III,IV	0.187	0.480	.007	22	view →
CESC	OS	Tertile	II,III,IV	0.922	0.735	.008	16	view →
DLBC	OS	Quartile	All	0.518	1.000	.003	14	view →
READ	DFS	Median	IV	0.179	0.936	.010	9	view →
ESCA	OS	Quartile	III,IV	0.755	0.499	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

CDC42P3–UCEC (OS)

Open the UCEC breakdown →