Q-omics provides the consensus-scored CDC42P1 profile across patient tissues and cancer cell-line models. CDC42P1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in LAML. Among the 18 cancer types available for tumor–normal comparison, CDC42P1 is differentially expressed in 5, with the highest sampling consensus in UCEC. Additionally, CDC42P1 RNA expression shows 8,227 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight LAML, UCEC, and GBM as cancer lineages where CDC42P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CDC42P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CDC42P1 survival associations across molecular data types. CDC42P1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CDC42P1 RNA expression–survival associations across cancer types. High CDC42P1 expression shows unfavorable associations in LUAD and SARC, but favorable associations in LAML, GBM, UCS and BLCA. The LAML Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify LAML as the clearest survival context for CDC42P1 RNA expression.
This table summarizes CDC42P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for CDC42P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CDC42P1 shows lower tumor expression in UCEC and higher tumor expression in BRCA, HNSC, LUAD and THCA. The UCEC box plot shows higher CDC42P1 RNA expression in normal versus tumor tissue (log2 FC = −0.320, t-test p = .003).
This table shows molecular features associated with CDC42P1 in patient tissues and cancer cell lines. In patient samples, CDC42P1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
