CDC42EP5

Across TCGA patient cohorts, CDC42EP5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,787 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC42EP5-associated genes across cancer lineages are NR2F2-AS1, MGP, and FBLN5. Each is linked with CDC42EP5 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDC42EP5-to-partner and partner-to-CDC42EP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC42EP5 versus NR2F2-AS1 in UCEC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP5→partner) and Y-score (partner→CDC42EP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NR2F2-AS1 →	+0.845	+0.400	.009	.007	3	7
CCRCC	MGP →	+1.663	+0.517	<.001	<.001	3	6
CCRCC	FBLN5 →	+1.210	+0.315	<.001	<.001	3	6
LUAD	GATA6 →	+0.612	+0.307	.001	<.001	3	6
OV	IGFBP7 →	+1.064	+0.613	<.001	.003	3	6
BRCA	TMEM119 →	+1.466	+0.734	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,787 associations by consensus.

CDC42EP5 vs NR2F2-AS1 — UCEC

Explore this scatter interactively →