CDC42EP3

Across TCGA cell cohorts, CDC42EP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,997 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDC42EP3-associated GO terms across cancer lineages are Regulation of cell-substrate adhesion, Regulation of intracellular protein transport, and Small GTPase-mediated signal transduction. Each is linked with CDC42EP3 in more than 15 cancer types. Because this analysis shows association rather than direction, both CDC42EP3-to-partner and partner-to-CDC42EP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-substrate adhesion grouped by CDC42EP3-low versus CDC42EP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP3→partner) and Y-score (partner→CDC42EP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-substrate adhesion →	+0.136	+3.080	<.001	<.001	3	16
LARGE_INTESTINE	Regulation of intracellular protein transport →	+0.072	+1.491	<.001	<.001	3	15
URINARY_TRACT	Small GTPase-mediated signal transduction →	+0.057	+1.443	.003	.003	2	15
UPPER_AERODIGESTIVE_TRACT	Regulation of protein K48-linked ubiquitination →	+0.156	+1.452	.001	<.001	3	14
URINARY_TRACT	Cellular response to abiotic stimulus →	+0.047	+1.832	.001	.001	3	14
BONE	Wound healing →	+0.137	+3.435	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,997 associations by consensus.

Regulation of cell-substrate adhesion by CDC42EP3 expression — BONE

Explore this box plot interactively →