CDC42EP2

Across TCGA patient cohorts, CDC42EP2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,001 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC42EP2-associated genes across cancer lineages are DDR2, CNRIP1, and SVEP1. Each is linked with CDC42EP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDC42EP2-to-partner and partner-to-CDC42EP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC42EP2 versus DDR2 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP2→partner) and Y-score (partner→CDC42EP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDR2 →	+1.110	+0.316	.006	.005	3	6
BRCA	CNRIP1 →	+0.884	+0.406	<.001	<.001	3	6
CCRCC	SVEP1 →	+1.136	+0.332	<.001	<.001	3	6
BRCA	CLMP →	+0.925	+0.235	<.001	<.001	3	5
UCEC	MRGPRF →	+1.266	+0.460	<.001	<.001	3	5
OV	BGN →	+1.336	+0.256	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,001 associations by consensus.

CDC42EP2 vs DDR2 — OV

Explore this scatter interactively →