CDC42EP2

Across TCGA patient cohorts, CDC42EP2 mutation is significantly associated with the RNA expression of many other genes, with 326 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42EP2-associated genes across cancer lineages are MICG, RN7SL865P, and EPPIN-WFDC6. Each is linked with CDC42EP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42EP2-to-partner and partner-to-CDC42EP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MICG grouped by CDC42EP2-low versus CDC42EP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP2→partner) and Y-score (partner→CDC42EP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MICG →	+0.639	+2.789	.002	.008	3	1
SKCM	RN7SL865P →	+0.061	+5.225	<.001	.001	3	1
SKCM	EPPIN-WFDC6 →	+0.023	+3.943	.001	.002	3	1
SKCM	ARHGEF38-IT1 →	+0.110	+3.717	<.001	.001	3	1
UCEC	HERC2P7 →	+0.087	+2.429	<.001	.007	3	1
UCEC	PES1 →	+0.677	+3.459	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 326 associations by consensus.

MICG by CDC42EP2 expression — SKCM

Explore this box plot interactively →