CDC42EP2

Across TCGA cell cohorts, CDC42EP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,630 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDC42EP2-associated GO terms across cancer lineages are Positive regulation of natural killer cell mediated immune response to tumor cell, Positive regulation of actin filament polymerization, and Regulation of pseudopodium assembly. Each is linked with CDC42EP2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDC42EP2-to-partner and partner-to-CDC42EP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of natural killer cell mediated immune response to tumor cell grouped by CDC42EP2-low versus CDC42EP2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP2→partner) and Y-score (partner→CDC42EP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of natural killer cell mediated immune response to tumor cell →	+0.216	+0.960	<.001	<.001	3	9
LARGE_INTESTINE	Positive regulation of actin filament polymerization →	+0.098	+0.982	<.001	<.001	3	9
PANCREAS	Regulation of pseudopodium assembly →	+0.139	+1.206	<.001	<.001	3	9
PANCREAS	Positive regulation of pseudopodium assembly →	+0.139	+1.206	<.001	<.001	3	9
BONE	Protein localization to membrane →	+0.076	+1.274	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Regulation of fibroblast proliferation →	+0.086	+1.058	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,630 associations by consensus.

Positive regulation of natural killer cell mediated immune response to tumor cell by CDC42EP2 expression — LARGE_INTESTINE

Explore this box plot interactively →