CDC42EP2

Across TCGA cell cohorts, CDC42EP2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CDC42EP2-associated genes across cancer lineages are ADAM2, OR2T2, and ASB10. Each is linked with CDC42EP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42EP2-to-partner and partner-to-CDC42EP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM2 grouped by CDC42EP2-low versus CDC42EP2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP2→partner) and Y-score (partner→CDC42EP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ADAM2 →	+0.006	+6.022	<.001	.001	3	1
SKIN	OR2T2 →	+0.013	+4.977	<.001	.007	3	1
BLOOD_Leukemia	ASB10 →	+0.082	+4.551	<.001	.004	3	1
BLOOD_Leukemia	SCGB1C1 →	+0.098	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ADAM2 by CDC42EP2 expression — SKIN

Explore this box plot interactively →