CDC42EP2

Across TCGA cell cohorts, CDC42EP2 mutation is significantly associated with the mutation status of many other genes, with 2,059 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDC42EP2-associated genes across cancer lineages are NPAS3, ASTN1, and CWF19L2. Each is linked with CDC42EP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42EP2-to-partner and partner-to-CDC42EP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPAS3 grouped by CDC42EP2-low versus CDC42EP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP2→partner) and Y-score (partner→CDC42EP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NPAS3 →	+3.635	+3.635	.003	.003	1	2
BLOOD_Leukemia	ASTN1 →	+2.880	+3.495	.002	.002	1	2
SKIN	CWF19L2 →	+4.392	+4.392	.009	.009	1	2
BLOOD_Leukemia	AFF2 →	+3.050	+3.247	.008	.008	1	2
BLOOD_Leukemia	DIP2A →	+2.728	+3.375	.003	.003	1	2
BLOOD_Leukemia	NEK8 →	+3.050	+3.247	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,059 associations by consensus.

NPAS3 by CDC42EP2 expression — BLOOD_Leukemia

Explore this box plot interactively →