CDC42BPG

Across TCGA pan-cancer cohorts, CDC42BPG mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CDC42BPG data layer compared with 24 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CDC42BPG mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CDC42BPG expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where CDC42BPG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.424	.003	52	view →
CCRCC	DFS	Median	All	0.865	0.624	.003	15	view →
HNSC	DFS	Median	II,III,IV	0.745	0.539	.009	12	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.863	.034	2	view →
PDAC	DFS	Quartile	II,III,IV	0.951	0.731	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CDC42BPG–UCEC (DFS)

Open the UCEC breakdown →