Across TCGA patient cohorts, CDC42BPB protein abundance is significantly associated with the RNA expression of many other genes, with 18,518 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDC42BPB-associated genes across cancer lineages are ZFYVE21, CINP, and GOLGA5. Each is linked with CDC42BPB in more than 8 cancer types. Because this analysis shows association rather than direction, both CDC42BPB-to-partner and partner-to-CDC42BPB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPB→partner) and Y-score (partner→CDC42BPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZFYVE21 →	+0.558	+0.283	<.001	<.001	3	9
OV	CINP →	+0.698	+0.171	<.001	.001	3	9
HNSC	GOLGA5 →	+0.803	+0.260	.002	<.001	3	9
OV	VTI1B →	+0.602	+0.255	<.001	<.001	3	8
GBM	MAP4K5 →	+0.692	+0.230	<.001	<.001	3	8
BRCA	AKT1 →	+0.980	+0.420	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,518 associations by consensus.

Exploration

CDC42BPB survival (RNA) · tumor vs normal (RNA) · all CDC42BPB data types