Across TCGA patient cohorts, CDC42BPB mutation is significantly associated with the RNA expression of many other genes, with 4,766 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42BPB-associated genes across cancer lineages are TSPAN7, GPI, and LINC00865. Each is linked with CDC42BPB in more than 3 cancer types. Because this analysis shows association rather than direction, both CDC42BPB-to-partner and partner-to-CDC42BPB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPB→partner) and Y-score (partner→CDC42BPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSPAN7 →	-0.879	-1.237	<.001	.002	3	4
UCEC	GPI →	+0.348	+2.483	.001	<.001	3	4
UCEC	LINC00865 →	-0.437	-1.247	.005	.002	3	4
CESC	COA4 →	+0.482	+3.351	.005	.005	3	3
SKCM	UQCRC1 →	+0.541	+2.434	<.001	.001	3	3
SKCM	FAM207A →	+0.616	+3.334	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,766 associations by consensus.

Exploration

CDC42BPB survival (RNA) · tumor vs normal (RNA) · all CDC42BPB data types