CDC42BPB

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDC42BPB mutation is significantly associated with the total protein of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42BPB-associated genes across cancer lineages are HER2, 14-3-3_beta, and MEK1. Each is linked with CDC42BPB in more than 3 cancer types. Because this analysis shows association rather than direction, both CDC42BPB-to-partner and partner-to-CDC42BPB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPB→partner) and Y-score (partner→CDC42BPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHER2 →+0.250+2.807.046.00234
UCEC14-3-3_beta →-0.098-1.847<.001.00132
UCECMEK1 →+0.408+2.129<.001<.00132
UCECPCNA →+0.144+1.206.015.00932
UCECPDCD4 →-0.389-1.513.002.00632
UCECShc_pY317 →-0.138-1.415<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

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