Across TCGA cell cohorts, CDC42BPB mutation is significantly associated with the RNA expression of many other genes, with 802 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDC42BPB-associated genes across cancer lineages are LY6G6F, NDUFV1, and NUDT8. Each is linked with CDC42BPB in more than 2 cancer types. Because this analysis shows association rather than direction, both CDC42BPB-to-partner and partner-to-CDC42BPB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPB→partner) and Y-score (partner→CDC42BPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LY6G6F →	+0.040	+5.087	<.001	.004	3	2
OESOPHAGUS	NDUFV1 →	+0.702	+2.944	.006	.007	2	3
OESOPHAGUS	NUDT8 →	+1.484	+3.000	<.001	.007	3	2
SOFT_TISSUE	PPIAL4D →	+0.105	+3.999	<.001	.004	3	2
BLOOD_Lymphoma	TLE7 →	+0.009	+4.058	<.001	.009	3	2
LARGE_INTESTINE	OGFOD2 →	+0.401	+3.169	.005	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 802 associations by consensus.

Exploration

CDC42BPB survival (RNA) · tumor vs normal (RNA) · all CDC42BPB data types