CDC42BPA

Across TCGA patient cohorts, CDC42BPA mutation is significantly associated with the RNA expression of many other genes, with 5,811 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42BPA-associated genes across cancer lineages are FANCA, CDT1, and PTTG1. Each is linked with CDC42BPA in more than 4 cancer types. Because this analysis shows association rather than direction, both CDC42BPA-to-partner and partner-to-CDC42BPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FANCA grouped by CDC42BPA-low versus CDC42BPA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPA→partner) and Y-score (partner→CDC42BPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FANCA →	+0.709	+2.104	<.001	<.001	3	5
UCEC	CDT1 →	+0.741	+2.136	<.001	<.001	3	4
UCEC	PTTG1 →	+0.596	+3.470	<.001	<.001	3	4
UCEC	PSAT1P4 →	+0.091	+1.180	.001	.002	3	4
SKCM	FTH1P15 →	+0.503	+3.635	<.001	.001	3	4
CESC	OR4H12P →	+0.010	+4.415	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,811 associations by consensus.

FANCA by CDC42BPA expression — UCEC

Explore this box plot interactively →