CDC42BPA

Across TCGA cell cohorts, CDC42BPA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,661 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CDC42BPA-associated GO terms across cancer lineages are Golgi vesicle transport, Vesicle tethering, and Regulation of microtubule polymerization or depolymerization. Each is linked with CDC42BPA in more than 12 cancer types. Because this analysis shows association rather than direction, both CDC42BPA-to-partner and partner-to-CDC42BPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by CDC42BPA-low versus CDC42BPA-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPA→partner) and Y-score (partner→CDC42BPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.073	+1.050	.001	<.001	3	13
LUNG_SCLC	Vesicle tethering →	+0.092	+0.806	.001	<.001	3	12
OVARY	Regulation of microtubule polymerization or depolymerization →	+0.066	+0.786	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.069	+0.849	.005	.008	2	12
OESOPHAGUS	Post-Golgi vesicle-mediated transport →	+0.095	+1.011	<.001	<.001	2	12
BLOOD_Lymphoma	Response to UV →	+0.051	+1.811	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,661 associations by consensus.

Golgi vesicle transport by CDC42BPA expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →