CDC42BPA

Across TCGA cell cohorts, CDC42BPA mutation is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDC42BPA-associated genes across cancer lineages are RETN, ACSM2B, and ODAM. Each is linked with CDC42BPA in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42BPA-to-partner and partner-to-CDC42BPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RETN grouped by CDC42BPA-low versus CDC42BPA-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPA→partner) and Y-score (partner→CDC42BPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RETN →	+2.624	+3.351	.006	.005	3	2
LUNG_NSCLC_LUAD	ACSM2B →	+0.026	+3.887	<.001	.002	3	2
KIDNEY	ODAM →	+0.038	+4.491	<.001	.002	3	1
KIDNEY	MYF6 →	+0.022	+4.121	.001	.006	3	1
KIDNEY	TBX22 →	+0.034	+4.121	.001	.006	3	1
OESOPHAGUS	SLC17A1 →	+0.017	+3.392	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

RETN by CDC42BPA expression — BLOOD_Leukemia

Explore this box plot interactively →