CDC42

Across TCGA patient cohorts, CDC42 protein abundance is significantly associated with the RNA expression of many other genes, with 6,466 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CDC42-associated genes across cancer lineages are FCGR3B, IFFO2, and RNU6-87P. Each is linked with CDC42 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDC42-to-partner and partner-to-CDC42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC42 versus FCGR3B in LUAD, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42→partner) and Y-score (partner→CDC42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FCGR3B →	-0.923	-0.195	.005	<.001	3	3
HNSC	IFFO2 →	+0.779	+0.273	.001	.005	3	3
UCEC	RNU6-87P →	+1.168	+0.290	.004	<.001	3	3
UCEC	VCAN →	-0.941	-0.242	<.001	.003	3	3
UCEC	FAP →	-1.044	-0.312	<.001	.001	3	3
UCEC	CCDC80 →	-1.425	-0.337	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,466 associations by consensus.

CDC42 vs FCGR3B — LUAD

Explore this scatter interactively →