CDC40

Across TCGA patient cohorts, CDC40 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,329 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC40-associated proteins across cancer lineages are SCAF8, VTA1, and PPIL4. Each is linked with CDC40 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDC40-to-partner and partner-to-CDC40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC40 versus SCAF8 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC40→partner) and Y-score (partner→CDC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SCAF8 →	+0.244	+0.521	<.001	<.001	3	6
OV	VTA1 →	+0.389	+0.520	.007	.001	1	7
GBM	PPIL4 →	+0.315	+0.369	<.001	.002	3	5
GBM	SYNCRIP →	+0.371	+0.410	<.001	<.001	3	5
OV	DRG2 →	+0.288	+0.479	.002	.001	3	5
BRCA	HDDC2 →	+0.351	+0.412	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,329 associations by consensus.

CDC40 vs SCAF8 — LSCC

Explore this scatter interactively →