CDC40

Across TCGA patient cohorts, CDC40 protein abundance is significantly associated with the RNA expression of many other genes, with 13,676 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC40-associated genes across cancer lineages are ZBTB24, NUP43, and QRSL1. Each is linked with CDC40 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDC40-to-partner and partner-to-CDC40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC40 versus ZBTB24 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC40→partner) and Y-score (partner→CDC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZBTB24 →	+0.531	+0.247	<.001	.002	3	8
HNSC	NUP43 →	+0.618	+0.146	<.001	<.001	3	8
BRCA	QRSL1 →	+0.699	+0.293	<.001	<.001	3	8
UCEC	COQ3 →	+0.800	+0.180	<.001	<.001	3	8
BRCA	SMPD2 →	+0.798	+0.360	<.001	<.001	3	8
GBM	HDAC2 →	+0.802	+0.405	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,676 associations by consensus.

CDC40 vs ZBTB24 — OV

Explore this scatter interactively →