CDC40

Across TCGA patient cohorts, CDC40 protein abundance is significantly associated with the protein abundance of many other proteins, with 26,018 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDC40-associated proteins across cancer lineages are RNF20, SF3A1, and SF3B1. Each is linked with CDC40 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDC40-to-partner and partner-to-CDC40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC40 versus RNF20 in GBM, with a Pearson correlation of 0.66.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC40→partner) and Y-score (partner→CDC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNF20 →	+0.226	+0.314	<.001	<.001	3	10
GBM	SF3A1 →	+0.276	+0.330	<.001	<.001	3	10
GBM	SF3B1 →	+0.254	+0.320	<.001	<.001	3	10
GBM	SF3B2 →	+0.263	+0.310	<.001	<.001	3	10
GBM	SFPQ →	+0.289	+0.329	<.001	<.001	3	10
BRCA	SMC3 →	+0.355	+0.319	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,018 associations by consensus.

CDC40 vs RNF20 — GBM

Explore this scatter interactively →