CDC37L1

Across TCGA pan-cancer cohorts, CDC37L1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CDC37L1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CDC37L1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CDC37L1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

LUAD, COAD, and LSCC are the cancer types where CDC37L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	1.000	0.862	.004	16	view →
COAD	DFS	Median	II,III,IV	1.000	0.916	.035	12	view →
LSCC	OS	Median	All	1.000	0.937	.010	8	view →
HNSC	DFS	Quartile	III,IV	1.000	0.869	.016	6	view →
PDAC	OS	Tertile	III,IV	0.384	0.802	.035	2	view →
CCRCC	OS	Quartile	II,III,IV	1.000	0.659	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CDC37L1–LUAD (OS)

Open the LUAD breakdown →