CDC37L1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CDC37L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,035 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CDC37L1-associated GO terms across cancer lineages are Regulation of intracellular steroid hormone receptor signaling pathway, Positive regulation of neutrophil activation, and Regulation of post-transcriptional gene silencing. Each is linked with CDC37L1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDC37L1-to-partner and partner-to-CDC37L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular steroid hormone receptor signaling pathway grouped by CDC37L1-low versus CDC37L1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC37L1→partner) and Y-score (partner→CDC37L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTRegulation of intracellular steroid hormone receptor signaling pathway →+0.096+0.919<.001.001310
LUNG_NSCLC_LUSCPositive regulation of neutrophil activation →+1.468+1.226<.001<.00139
CNSRegulation of post-transcriptional gene silencing →+0.091+0.587<.001<.00139
BLOOD_LymphomaGolgi organization →+0.051+0.908<.001.00139
KIDNEYProtein sumoylation →+0.055+0.806.008.00729
KIDNEYPositive regulation of type B pancreatic cell development →-0.249-0.822<.001.00429
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,035 associations by consensus.

Regulation of intracellular steroid hormone receptor signaling pathway by CDC37L1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Regulation of intracellular steroid hormone receptor signaling pathway in CDC37L1-low vs CDC37L1-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration