CDC37L1-DT

Across TCGA pan-cancer cohorts, CDC37L1-DT RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CDC37L1-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CDC37L1-DT RNA is repressed in tumor relative to normal tissue. In most cancer types CDC37L1-DT is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where CDC37L1-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDC37L1-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	All	−1.104	<.001	11	view →
KIRC	Male	All	−0.954	<.001	11	view →
KICH	Female	II,III,IV	−2.158	<.001	10	view →
THCA	All	All	−0.482	<.001	7	view →
LUAD	All	II,III,IV	−0.447	<.001	7	view →
BRCA	Female	II,III,IV	−0.450	<.001	6	view →
HNSC	All	All	−0.241	.013	6	view →
LUSC	All	III,IV	−0.778	.007	4	view →
BLCA	Female	IV	+1.250	.040	1	view →
LIHC	All	All	−0.219	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CDC37L1-DT–KIRP

Open the KIRP breakdown →