CDC37

Across TCGA patient cohorts, CDC37 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,434 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC37-associated proteins across cancer lineages are KEAP1, CARM1, and RRBP1. Each is linked with CDC37 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDC37-to-partner and partner-to-CDC37 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC37 versus KEAP1 in OV, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC37→partner) and Y-score (partner→CDC37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KEAP1 →	+0.436	+0.538	<.001	<.001	3	6
BRCA	CARM1 →	+0.403	+0.545	<.001	<.001	3	5
CCRCC	RRBP1 →	-0.361	-0.238	<.001	<.001	3	4
LUAD	SEC11C →	-0.723	-0.240	<.001	.001	3	4
CCRCC	HSP90B1 →	-0.307	-0.228	<.001	<.001	3	4
LUAD	HSPA5 →	-0.276	-0.307	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,434 associations by consensus.

CDC37 vs KEAP1 — OV

Explore this scatter interactively →