CDC37

Across TCGA patient cohorts, CDC37 protein abundance is significantly associated with the RNA expression of many other genes, with 7,881 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CDC37-associated genes across cancer lineages are MRPL4, HAUS8, and UBL5. Each is linked with CDC37 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDC37-to-partner and partner-to-CDC37 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC37 versus MRPL4 in OV, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC37→partner) and Y-score (partner→CDC37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRPL4 →	+0.785	+0.443	<.001	<.001	3	7
BRCA	HAUS8 →	+0.656	+0.213	<.001	.004	3	6
UCEC	UBL5 →	+0.792	+0.257	<.001	<.001	3	6
BRCA	DNM2 →	+0.518	+0.248	<.001	<.001	3	6
BRCA	TYK2 →	+0.500	+0.192	.002	.003	3	5
OV	ELOF1 →	+0.540	+0.372	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,881 associations by consensus.

CDC37 vs MRPL4 — OV

Explore this scatter interactively →