CDC37

Across TCGA patient cohorts, CDC37 mutation is significantly associated with the RNA expression of many other genes, with 1,204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC37-associated genes across cancer lineages are SNORD114-13, SNORA10B, and RNU2-50P. Each is linked with CDC37 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC37-to-partner and partner-to-CDC37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-13 grouped by CDC37-low versus CDC37-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC37→partner) and Y-score (partner→CDC37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNORD114-13 →	+0.743	+5.142	<.001	.002	3	2
SKCM	SNORA10B →	+0.328	+4.979	<.001	<.001	3	2
SKCM	RNU2-50P →	+0.260	+3.923	<.001	.003	3	2
CESC	RN7SKP94 →	+0.226	+6.569	<.001	.001	3	2
CESC	LINC01745 →	+0.441	+6.342	<.001	.001	3	2
GBM	RN7SL55P →	+0.209	+5.149	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,204 associations by consensus.

SNORD114-13 by CDC37 expression — COAD

Explore this box plot interactively →