CDC27

Across TCGA patient cohorts, CDC27 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,303 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC27-associated proteins across cancer lineages are CCDC43, NPEPPS, and KPNA2. Each is linked with CDC27 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDC27-to-partner and partner-to-CDC27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC27 versus CCDC43 in PDAC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC27→partner) and Y-score (partner→CDC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CCDC43 →	+0.439	+0.341	<.001	.002	3	6
OV	NPEPPS →	+0.293	+0.420	.001	.002	3	5
LSCC	KPNA2 →	+0.522	+0.401	<.001	<.001	3	5
GBM	TAOK1 →	+0.227	+0.404	.003	<.001	3	5
LUAD	NCAPG →	+0.592	+0.366	<.001	<.001	3	5
LSCC	NUFIP2 →	+0.238	+0.526	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,303 associations by consensus.

CDC27 vs CCDC43 — PDAC

Explore this scatter interactively →