CDC27

Across TCGA patient cohorts, CDC27 protein abundance is significantly associated with the RNA expression of many other genes, with 12,381 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC27-associated genes across cancer lineages are KPNB1, CENPI, and NCAPG. Each is linked with CDC27 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDC27-to-partner and partner-to-CDC27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC27 versus KPNB1 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC27→partner) and Y-score (partner→CDC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KPNB1 →	+0.530	+0.270	<.001	<.001	3	9
UCEC	CENPI →	+0.998	+0.234	<.001	<.001	3	8
GBM	NCAPG →	+0.966	+0.137	<.001	.004	3	8
UCEC	RAD51AP1 →	+0.869	+0.193	.001	<.001	3	8
UCEC	NCAPH →	+1.045	+0.251	<.001	<.001	3	8
GBM	HJURP →	+1.224	+0.209	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,381 associations by consensus.

CDC27 vs KPNB1 — BRCA

Explore this scatter interactively →