CDC27

Across TCGA patient cohorts, CDC27 mutation is significantly associated with the RNA expression of many other genes, with 3,504 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC27-associated genes across cancer lineages are RNU1-57P, BPY2DP, and ATP5F1AP8. Each is linked with CDC27 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC27-to-partner and partner-to-CDC27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-57P grouped by CDC27-low versus CDC27-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC27→partner) and Y-score (partner→CDC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU1-57P →	+0.426	+5.026	<.001	.009	3	2
STAD	BPY2DP →	+0.331	+5.105	<.001	.008	3	2
CESC	ATP5F1AP8 →	+0.025	+5.003	<.001	<.001	3	2
CESC	RPL35AP37 →	+0.099	+4.196	<.001	.003	3	2
CESC	RNA5SP198 →	+0.241	+4.559	<.001	.006	3	2
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,504 associations by consensus.

RNU1-57P by CDC27 expression — STAD

Explore this box plot interactively →