CDC27

Across TCGA cell cohorts, CDC27 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,844 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDC27-associated GO terms across cancer lineages are Positive regulation of cell cycle, Regulation of cytokinesis, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with CDC27 in more than 17 cancer types. Because this analysis shows association rather than direction, both CDC27-to-partner and partner-to-CDC27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle grouped by CDC27-low versus CDC27-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC27→partner) and Y-score (partner→CDC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of cell cycle →	+0.077	+0.791	<.001	<.001	3	18
SOFT_TISSUE	Regulation of cytokinesis →	+0.101	+0.797	<.001	<.001	3	18
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.124	+0.899	<.001	<.001	3	17
BLOOD_Myeloma	DNA replication →	+0.117	+0.792	<.001	<.001	3	17
BLOOD_Myeloma	Nuclear chromosome segregation →	+0.133	+1.071	<.001	<.001	3	17
STOMACH	Positive regulation of cytokinesis →	+0.130	+0.996	.002	<.001	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,844 associations by consensus.

Positive regulation of cell cycle by CDC27 expression — KIDNEY

Explore this box plot interactively →