CDC27

Across TCGA cell cohorts, CDC27 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CDC27-associated genes across cancer lineages are IL1F10, OPN1MW3, and LUZP4. Each is linked with CDC27 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC27-to-partner and partner-to-CDC27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL1F10 grouped by CDC27-low versus CDC27-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC27→partner) and Y-score (partner→CDC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	IL1F10 →	+0.116	+4.095	<.001	.009	3	1
SKIN	OPN1MW3 →	+0.010	+5.022	<.001	.002	3	1
BLOOD_Lymphoma	LUZP4 →	+0.103	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	NEUROD4 →	+0.156	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	PLCZ1 →	+0.127	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	RIPPLY1 →	+0.046	+4.191	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

IL1F10 by CDC27 expression — SKIN

Explore this box plot interactively →