CDC26

Across TCGA cell cohorts, CDC26 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,304 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CDC26-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Proteasome regulatory particle assembly, and Positive regulation of chromosome condensation. Each is linked with CDC26 in more than 16 cancer types. Because this analysis shows association rather than direction, both CDC26-to-partner and partner-to-CDC26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by CDC26-low versus CDC26-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC26→partner) and Y-score (partner→CDC26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Immunoglobulin heavy chain V-D-J recombination →	+0.202	+0.877	<.001	.003	3	17
OVARY	Proteasome regulatory particle assembly →	+0.122	+0.679	<.001	<.001	3	14
SOFT_TISSUE	Positive regulation of chromosome condensation →	+0.217	+0.973	<.001	<.001	3	13
SOFT_TISSUE	Somatic recombination of immunoglobulin gene segments →	+0.078	+0.785	<.001	.001	3	12
KIDNEY	Protein localization to condensed chromosome →	+0.117	+0.410	<.001	.003	3	11
SOFT_TISSUE	Immunoglobulin V(D)J recombination →	+0.137	+0.835	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,304 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by CDC26 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →