CDC25A

Across TCGA cell cohorts, CDC25A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,626 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CDC25A-associated GO terms across cancer lineages are Positive regulation of G2/MI transition of meiotic cell cycle, DNA replication initiation, and DNA strand elongation involved in DNA replication. Each is linked with CDC25A in more than 19 cancer types. Because this analysis shows association rather than direction, both CDC25A-to-partner and partner-to-CDC25A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of G2/MI transition of meiotic cell cycle grouped by CDC25A-low versus CDC25A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC25A→partner) and Y-score (partner→CDC25A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of G2/MI transition of meiotic cell cycle →	+0.198	+1.171	<.001	<.001	3	20
BONE	DNA replication initiation →	+0.197	+1.451	<.001	<.001	3	20
OESOPHAGUS	DNA strand elongation involved in DNA replication →	+0.239	+1.252	<.001	<.001	3	20
OESOPHAGUS	DNA-templated transcription termination →	+0.105	+1.048	.001	.008	3	20
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.283	+1.589	<.001	<.001	3	19
OESOPHAGUS	DNA replication checkpoint signaling →	+0.245	+1.343	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,626 associations by consensus.

Positive regulation of G2/MI transition of meiotic cell cycle by CDC25A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →